C4B Binding Protein

Synonyms

• C4B BINDING PROTEIN
• C4BP
• LAB11074

Cerner Name

C4B Binding Protein

Clinical Info

Confirmation and characterization of protein S (PS) deficiency: C4b-binding protein elevates as an acute phase protein that may lead to enhanced protein S binding and decreased free protein S levels.

Specimen Sources

Blood, Arterial Blood, Capillary Blood, Central Line Blood, Venous

Specimen Types

Blood

Container

ESR

Collection Instructions

Container/Tube:  Light blue-top (3.2% sodium citrate) tube
Specimen:   1 mL plasma (0.5mL min)
 
Collection: Citrated plasma samples should be collected by double centrifugation. Blood should be collected in a blue-top tube containing 3.2% buffered sodium citrate. Evacuated collection tubes must be filled to completion to ensure a proper blood to anticoagulant ratio. The sample should be mixed immediately by gentle inversion at least six times to ensure adequate mixing of the anticoagulant with the blood. A discard tube is not required prior to collection of coagulation samples, except when using a winged blood collection device (ie, "butterfly"), in which case a discard tube should be used. When non citrate tubes are collected for other tests, collect sterile and nonadditive (red-top) tubes prior to citrate (blue-top) tubes. Any tube containing an alternate anticoagulant should be collected after the blue-top tube. Gel-barrier tubes and serum tubes with clot initiators should also be collected after the citrate tubes. Centrifuge for 10 minutes and carefully remove 2/3 of the plasma using a plastic transfer pipette, being careful not to disturb the cells. Deliver to a plastic transport tube, cap, and recentrifuge for 10 minutes. Use a second plastic pipette to remove the plasma, staying clear of the platelets at the bottom of the tube.

Specimen Volume

1 mL plasma (0.5mL min)

Transport Instructions

Frozen plasma

Specimen Stability

8 Hours Room Temperature
14 Days Frozen

Methodology

Enzyme-linked immunosorbent assay (ELISA)

Days Performed

TAT: 5-9 Days

Performing Laboratory

Esoterix Endocrinology

CPT

83520

PDM

5601085

Only Orderable at Locations:

Orderable Everywhere

Results

Result Interpretation

Forms