Lymphocyte Proliferation to Mitogens

Synonyms

  • LAB10844
  • LYMPHOCYTE MITOGEN PROLIF

Cerner Name

Lymphocyte Mitogen Prolif

Clinical Info

Assessing T-cell function in patients on immunosuppressive therapy, including solid-organ transplant patients
Evaluating patients suspected of having impairment in cellular immunity
Evaluation of T-cell function in patients with primary immunodeficiencies, either cellular (DiGeorge syndrome, T-negative severe combined immunodeficiency: SCID, etc) or combined T- and B-cell immunodeficiencies (T- and B-negative SCID, Wiskott Aldrich syndrome, ataxia telangiectasia, common variable immunodeficiency, among others) where T-cell function may be impaired
Evaluation of T-cell function in patients with secondary immunodeficiency, either disease related or iatrogenic
Evaluation of recovery of T-cell function and competence following bone marrow transplantation or hematopoietic stem cell transplantation

Specimen Sources

Blood, Arterial Blood, Capillary Blood, Central Line Blood, Venous

Specimen Types

Blood

Specimen Volume

Container

Green Top Tube

Collection Instructions

NOTE: DO NOT COLLECT FRIDAY, SATURDAY AND SUNDAYS
Container/Tube: Dark Green (Sodium Heparin) Tube
Specimen:
Less than 3 months: 1 mL
3 months-5 years: 2 mL
6-18 years: 3 mL
Greater than 18 years: 10 mL
Minimum Volume: 1 mL whole blood
Stability: 24 Hrs Room Temperature
Collection Instructions: Send specimen is original tube. Do not aliquot.

Transport Instructions

Specimen Stability

24 Hrs Room Temperature

Methodology

Flow Cytometry

Days Performed

Monday through Friday

Performing Laboratories

Mayo Medial Laboratories
NOTE: DO NOT COLLECT FRIDAY, SATURDAY AND SUNDAYS

CPT

86353
86353 (if appropriate)
LOINC Code: 69018-0

PDM

5901660

Results

Component Name Base Name Common Name External Name
LYMPHOCYTE MITOGEN PROFILE LYMPHMIT LYMPHOCYTE MITOGEN PROFILE Lymphocyte Mitogen Profile

Result Interpretation

Viability of lymphocytes at day 0: ≥75.0%

Maximum proliferation of phytohemagglutinin as % CD45:
≥49.9%

Maximum proliferation of phytohemagglutinin as % CD3:
≥58.5%

Maximum proliferation of pokeweed mitogen as % CD45:
≥4.5%

Forms

Immunology LAB10844 build edit