Clozapine Level

Synonyms

  • CLOZAPINE LEVEL
  • CLOZARIL
  • CLZ
  • FAZACLO
  • LAB10795
  • VERSACLOZ

Cerner Name

Clozapine Level

Clinical Info

Clozapine a tricyclic dibenzodiazepine derivative atypical antipsychotic agent used for treatment resistant schizophrenia and reducing suicidal behavior in schizophrenia and schizoaffective disorder

Specimen Sources

Blood, Arterial Blood, Capillary Blood, Central Line Blood, Venous

Specimen Types

Blood

Specimen Volume

Container

Red Top Tube

Collection Instructions

Specimen Red Top Tube (Red)
Specimen: 1 mL serum (0.5 mL min)
Trough samples (12 hrs after last dose) at steady state (3 Days after a dose change)
are recommended for testing clozapine.

Transport Instructions

Refrigerated

Specimen Stability

7 Days Room Temperature
7 Days Refrigerated
10 Months Frozen

Methodology

Homogenous Nanoparticle Agglutination Immunoassay

Days Performed

Monday-Sunday

Performing Laboratories

Northwell Health Laboratories

CPT

80159
LOINC Code: 6896-5

PDM

2153767

Results
Component Name Base Name Common Name External Name
CLOZAPINE (CLZ) CLOZAPINE CLOZAPINE CLZ Clozapine (CLZ)

Result Interpretation

350 – 600 ng/mL
There is no definitive Clozapine level that is associated with efficacy or toxicity. Efficacy for the majority of patients will be the highest at levels above 350 ng/mL.

Forms
Tox/TDM LAB10795 build edit