PROMETHEUS Anser IFX Build info

Synonyms

  • PROMETHEUS ANSER IFX
  • LAB10779

Short Name

PROMETHEUS ANSER IFX

Procedure Master Number

LAB10779

Procedure ID

114094

Clinical Info

This test is being discontinued Please order INFLIXIMAB
Serum concentrations of IFX may vary among equally dosed patients which can ultimately affect patient outcomes. Suboptimal levels of IFX have been linked to lower response rates in IBD patients. Furthermore, some patients may develop immunogenicity to IFX by producing antibodies to Infliximab (ATI). The presence of ATI has also been associated with increased rates of infusion reactions and drug clearance leading to lower response rates. Therefore, the quantitative measurement of IFX and ATI levels in serum provides healthcare providers with valuable information to help them gain a better understanding of the factors that may be affecting a patient’s loss of response.

The PROMETHEUS Anser VDZ test is a next generation and more sensitive quantitative monitoring assay that allows healthcare providers to measure and monitor serum VDZ and ATV levels at any time during therapy. Incorporating therapeutic drug monitoring may clarify what factors are contributing to a patient’s loss of response and help guide treatment decisions by providing information to help determine an appropriate course of action.

Specimen Type

Blood

Container

Gold Top Tube

Collection Instructions

Container/Tube:   Gold top tube
Specimen: 2 mL serum (0.5 ml min)
Transport Temperature:  Room Temperature
Stability:  7 days Room Temperature
                 7 Days  Refrigerated

Transport Instructions

Room Temperature

Specimen Stability

7 days Room Temperature
                 7 Days  Refrigerated

Methodology

Electrochemiluminescence Immunoassay (ECLIA)


Test Includes:
Serum Infliximab concentration (IFX) and Antibodies to Infliximab (IFX)

Days Performed

Monday - Friday
  TAT = 4 days from receipt at Prometheus Lab

Performing Laboratory

Prometheus Therapeutics & Diagnostics

CPT

80145
82542

PDM

1759071

Results

Component Name Base Name Common Name External Name
PROMETHEUS LABORATORY FOOTER PROMLABFT PROMETHEUS LABORATORY FOOTER Prometheus Laboratory Footer
SERUM INFLIXIMAB (IFX) CONCENTRATION SERUMINFLIX SERUM INFLIXIMAB IFX CONCENTRATION Serum Infliximab (Ifx) Concentration
ANTIBODIES TO INFLIXIMAB (ATI) CONCENTRATION ATICONC ANTIBODIES TO INFLIXIMAB CONCENTRATION Antibodies To Infliximab (Ati) Concentration
PROMETHEUS ANSER IFX PROMANIFX PROMETHEUS ANSER IFX Prometheus Anser Ifx