CSF Pathogen Panel Molecular Detection

Synonyms

  • CEREBROSPINAL
  • CSF PCR PANEL
  • CSFPCR
  • ENCEPHALITIS
  • LAB10702
  • LP
  • LUMBAR PUNCTURE
  • ME PANEL
  • MENINGITIS

Cerner Name

CSF PCR Panel

Clinical Info

Intended for the multiplex PCR detection of multiple bacterial, viral, and fungal pathogens from cerebrospinal fluid in patients suspected of 
having encephalitis/meningitis. Targets include: Escherichia coli K1, Haemophilus influenzae, Listeria monocytogenes, Neisseria meningitidis 
(encapsulated), Streptococcus agalactiae, Streptococcus pneumoniae, Cytomegalovirus, Enterovirus, Herpes simplex virus 1, Herpes simplex 
virus 2, Human herpesvirus 6, Human parechovirus, Varicella zoster virus, and Cryptococcus neoformans/gattii.

Specimen Sources

CSF, Lumbar Puncture

Specimen Types

Body Fluid Cerebrospinal Fluid

Specimen Volume

0.5 mL of spinal fluid (Maintain sterility and forward promptly.)

Container

Primary tube preferred. A screw-capped, sterile vial. .

Collection Instructions

Container/Tube: A screw-capped, sterile vial-Primary tube preferred.
Specimen: 0.5 mL of spinal fluid (Maintain sterility and forward promptly.)
Transport Temperature: Refrigerated If there is a delay in transport of >24 hours, send specimen frozen in plastic vial.

Transport Instructions

Refrigerated If there is a delay in transport of >24 hours, send specimen frozen in plastic vial.

Specimen Stability

Room Temperature: 24 hours
Refrigerated: 7 days
Frozen 2 Years

Methodology

Multiplex Amplified nucleic acid test that uses Polymerase Chain Reaction (PCR)
 
Pathogens include:
Escherichia coli; Haemophilus influenzae; Listeria monocytogenes; Neisseria meningitidis; Streptococcus agalactiae; 
Streptococcus pneumoniae; CMV; Enterovirus; HSV-1; HSV-2; Human herpesvirus 6; Parechovirus; VZV and Cryptococcus. 

Days Performed

Monday through Sunday
 

Performing Laboratories

Northwell Health Laboratories

CPT

87483

PDM

1663066

Ordering Instructions

Intended for the multiplex PCR detection of multiple bacterial, viral, and fungal pathogens from cerebrospinal fluid in patients suspected of having encephalitis/meningitis. Targets include: Escherichia coli K1, Haemophilus influenzae, Listeria monocytogenes, Neisseria meningitidis (encapsulated), Streptococcus agalactiae, Streptococcus pneumoniae, Cytomegalovirus, Enterovirus, Herpes simplex virus 1, Herpes simplex virus 2, Human herpesvirus 6, Human parechovirus, Varicella zoster virus, and Cryptococcus neoformans/gattii.

Results
Component Name Base Name Common Name External Name
CSFPCR RESULT CSFPCRRSLT CSFPCR RSLT CSF PCR Panel
ESCHERICHIA COLI K1 ESCHERCOLIK1 ESCHERICHIA COLI K1 Escherichia coli K1
HAEMOPHILUS INFLUENZAE HAEMINFL HAEMOPHILUS INFLUENZAE Haemophilus influenzae
LISTERIA MONOCYTOGENES LISTERIA LISTERIA MONOCYTOGENES Listeria monocytogenes
NEISSERIA MENINGITIDIS (ENCAPSULATED) NMENINGIT NEISSERIA MENINGITIDIS ENCAPSULATED Neisseria meningitidis (encapsulated)
STREPTOCOCCUS AGALACTIAE STREPAGAL STREPAGAL, AGALACTIAE Streptococcus agalactiae
STREPTOCOCCUS PNEUMONIAE STREPPNEUM STREPPNEUM, PNEUMONIAE Streptococcus pneumoniae
CYTOMEGALOVIRUS CMV CYTOMEGALOVIRUS Cytomegalovirus
ENTEROVIRUS ENTEROVIRUS ENTEROVIRUS Enterovirus
HERPES SIMPLEX VIRUS 1 HSV1 HSV 1 Herpes simplex virus 1
HERPES SIMPLEX VIRUS 2 HSV2 HSV 2 Herpes simplex virus 2
HUMAN HERPES VIRUS 6 HSV6 HUMAN HERPES VIRUS 6 Human herpesvirus 6
HUMAN PARECHOVIRUS HPVPARECHO HUMAN PARECHOVIRUS Human parechovirus
VARICELLA ZOSTER VIRUS VZV VARICELLA ZOSTER VIRUS Varicella zoster virus
CRYPTOCOCCUS NEOFORMANS/GATTII CRYPTOCONEO CRYPTOCOCCUS NEOFORMANS GATTII Cryptococcus neoformans/gattii

Result Interpretation

Not Detected
 
Result should be interpreted in context of clinical presentation, imaging and other lab tests.  Positive predictive value may be lower in patients with normal CSF chemistry and cell count.

Forms
ID Molecular LAB10702 build edit