EPIC Test Compendium Alpha
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Encephalopathy, Autoimmune/Paraneoplastic Evaluation, Serum

Test Catalog Information

Test Catalog Synonyms
EPIC Synonyms	ENS2 Encephalopathy Autoimmune Eval, S
Cerner Primary Mnemonic	Encephalopathy Autoimmune Eval, S
EPIC Display Name	Encephalopathy, Autoimmune/Paraneoplastic Evaluation, Serum
Allscripts (AEHR) Order Name	Encephalopathy Autoimmune Eval, S
Sunrise Clinical Manager (SCM) Order Name	Encephalopathy, Autoimmune Evaluation, Serum
EPIC Inpatient Orderable	Yes
EPIC Outpatient Orderable	Yes
Cerner Results	NMDA-R AbCBA Amphiphysin Ab, S CASPR2-IgG CBA, S ANNA-2, S AGNA-1, S IFA Notes Purkinje Cell Cytoplasmic Ab Type 2 LGI1-IgG CBA, S GABA-B AbCBA Mglur1 Ab IFA, S NIF IFA, CSF Glutamic Acid Decarboxylase NMDA-R Ab CBA, CSF GFAP IFA, S AMPA-R AbCBA Encephalopathy, Interpretation, S ANNA-1, S Purkinje Cell Cytoplasmic Ab Type 1 PCA-Tr, S PCA-1, S PCA-2, S Reflex CRMP-5-IgG Western Blot, S NMDAR- AbCBAC Reflex Added ANNA-3, S Neurochondrin IFA, S Neuronal (V-G) K+ Channel Ab, S DPPX Ab IFA, S Neurochondrin IFA, CSF
Clinical Info	Mayo code ENS2 Evaluating new onset encephalopathy (noninfectious or metabolic) comprising confusional states, psychosis, delirium, memory loss, hallucinations, movement disorders, sensory or motor complaints, seizures, dyssomnias, ataxias, nausea, vomiting, inappropriate antidiuresis, coma, dysautonomias, or hypoventilation in serum specimens The following accompaniments should increase of suspicion for autoimmune encephalopathy: -Headache -Autoimmune stigmata (personal or family history or signs of diabetes mellitus, thyroid disorder, vitiligo, poliosis [premature graying], myasthenia gravis, rheumatoid arthritis, systemic lupus erythematosus) -History of cancer -Smoking history (20+ pack years) or other cancer risk factors -Inflammatory cerebral spinal fluid (or isolated protein elevation) -Neuroimaging signs suggesting inflammation Evaluating limbic encephalitis (noninfectious) Directing a focused search for cancer Investigating encephalopathy appearing in the course or wake of cancer therapy and not explainable by metastasis or drug effect
Specimen Type	Blood
Container	Red Top Tube
Collection Instructions	Container/Tube: Gold Top or Red Top Tube Specimen: 4.0 mL serum (2.5 mL min) Patient Preparation: 1. For optimal antibody detection, specimen collection is recommended prior to initiation of immunosuppressant medication or intravenous immunoglobulin treatment. 2. This test should not be requested in patients who have recently received radioisotopes, therapeutically or diagnostically, because of potential assay interference. The specific waiting period before specimen collection will depend on the isotope administered, the dose given, and the clearance rate in the individual patient. Specimens will be screened for radioactivity prior to analysis. Radioactive specimens received in the laboratory will be held 1 week and assayed if sufficiently decayed, or canceled if radioactivity remains. 3. Patient should have no general anesthetic or muscle-relaxant drugs in the previous 24 hours.
Transport Instructions	Refrigerated
Specimen Stability	72 Hours Room Temperature 28 Days Refrigerated or Frozen
Methodology	Indirect Immunofluorescence Assay (IFA) Cell-Binding Assay (CBA) Western Blot (WB) Immunoblot (IB) Radioimmunoassay (RIA)
Days Performed	TAT: 9-13 Days
Performing Laboratory	Mayo Clinic Laboratories in Rochester
CPT	86255 x 23 86341 LOINC Code: 94697-0
PDM	1759374

Desired Epic Build Encephalopathy, Autoimmune/Paraneoplastic Evaluation, Serum

Cerner Primary Mnemonic:

Encephalopathy Autoimmune Eval, S

PDM

1759374

Informatics - Workgroup

Immunology

Synonyms *

ENS2
Encephalopathy Autoimmune Eval, S

Display Name *

Encephalopathy, Autoimmune/Paraneoplastic Evaluation, Serum

Order Entry Specimen Sources *

Order Entry Specimen Types

Blood

Specimen Navigator Specimen Types

Specimen Navigator Specimen Sources

Specimen Navigator Short Name

Ordering info (EPIC SmartText)

Mayo code ENS2 Evaluating new onset encephalopathy (noninfectious or metabolic) comprising confusional states, psychosis, delirium, memory loss, hallucinations, movement disorders, sensory or motor complaints, seizures, dyssomnias, ataxias, nausea, vomiting, inappropriate antidiuresis, coma, dysautonomias, or hypoventilation in serum specimens The following accompaniments should increase of suspicion for autoimmune encephalopathy: -Headache -Autoimmune stigmata (personal or family history or signs of diabetes mellitus, thyroid disorder, vitiligo, poliosis [premature graying], myasthenia gravis, rheumatoid arthritis, systemic lupus erythematosus) -History of cancer -Smoking history (20+ pack years) or other cancer risk factors -Inflammatory cerebral spinal fluid (or isolated protein elevation) -Neuroimaging signs suggesting inflammation Evaluating limbic encephalitis (noninfectious) Directing a focused search for cancer Investigating encephalopathy appearing in the course or wake of cancer therapy and not explainable by metastasis or drug effect

IP Orderable

Yes

OP Orderable

Yes

AOEs *

AP AOEs

Special History

Build Comments

Filter *

Procedure Category Change

Cerner Results

Result Desc	Result display	Result PDM
NMDA-R AbCBA	NMDA-R AbCBA	1459836A
ENS1AMPHS	Amphiphysin Ab, S	1759374N
ENS1CS2CS	CASPR2-IgG CBA, S	1759374D
ENS1ANN2S	ANNA-2, S	1759374H
ENS1AGN1S	AGNA-1, S	1759374J
IFA Notes	IFA Notes	225304B
PCA2C	Purkinje Cell Cytoplasmic Ab Type 2	1659071F
ENS1LG1CS	LGI1-IgG CBA, S	1759374C
GABA-B AbCBA	GABA-B AbCBA	1459835A
Mglur1 Ab IFA, S	Mglur1 Ab IFA, S	1759374P
NIFIFAC	NIF IFA, CSF	2059435B
GAD	Glutamic Acid Decarboxylase	5910600
NMDAR AbCBAC	NMDA-R Ab CBA, CSF	1759170B
GFAP IFA, S	GFAP IFA, S	1759374Q
AMPA-R AbCBA	AMPA-R AbCBA	1459833A
ENS1AEESI	Encephalopathy, Interpretation, S	1759374A
ENS1ANN1S	ANNA-1, S	1759374F
PCA1C	Purkinje Cell Cytoplasmic Ab Type 1	1659071E
ENS1PCATR	PCA-Tr, S	1759374M
ENS1PCABP	PCA-1, S	1759374K
ENS1PCAB2	PCA-2, S	1759374L
REFLEXCRMP	Reflex CRMP-5-IgG Western Blot, S	5905943
NMDAR- AbCBAC	NMDAR- AbCBAC	1759170Z
Reflex Added	Reflex Added	1659071J
ENS1ANN3S	ANNA-3, S	1759374I
Neuroch IFA, S	Neurochondrin IFA, S	235274B
ENS1VGKC	Neuronal (V-G) K+ Channel Ab, S	1759374B
DPPX Ab IFA, S	DPPX Ab IFA, S	235274D
NCDIC	Neurochondrin IFA, CSF	225304C

Actual Epic build

Procedure Id

111704

Pdm

1759374

Order Display Name

Encephalopathy, Autoimmune/Paraneoplastic Evaluation, Serum

Procedure Name

ENCEPHALOPATHY AUTOIMMUNE EVAL, S

Procedure Master Number

LAB10600

Short Procedure Name

ENCEPHALOPATHY AUTOIMMUNE EVAL, S

Category Code

1.0

Category Code Record Name

LAB BLOOD ORDERABLES

Synonyms

ENS2 ENCEPHALOPATHY AUTOIMMUNE EVAL, S

Clinically Active

Yes

Orderable

Yes

Performable

Yes

Filter Genomics

Reference Link Url

https://labs.northwell.edu/epic/test/111704

Ordering Instructions

Default Specimen Type

Blood

Specimen Type Pick List

Blood

Specimen Type List

Op Specimen Type List

Specimen Source Pick List

Blood, Arterial Blood, Capillary Blood, Central Line Blood, Venous

Specimen Source Default - Male

Blood, Venous

Specimen Source Default - Female

Blood, Venous

Specimen Source List

Op Specimen Source List

Ip Lab Test Components For Report

Op Lab Test Components For Report

Order Questions

["3045300170", "3045300171", "3045300173"]

Order Questions Record Name

NH IP HOME COLLECT DATE NH IP HOME COLLECT DAYS NH IP HOME COLLECT MEDICALLY NECESSARY

Inpatient Order Questions

[]

Inpatient Order Questions Record Name

Order Specific Question Override

Yes

Inpatient Question Override

Location Restrict List Ip

Location Restrict List Ip Record Name

Location Restrict List Include Ip

Location Restrict List Op

Location Restrict List Op Record Name

Location Restrict List Includes Op

Edp Amb Order Specific Questions Record Name

Edp Ip Order Specific Questions Record Name

Edp Ip Specimen Source

Blood, Venous Blood, Central Line Blood, Arterial Blood, Capillary

Edp Op Specimen Source

Edp Ip Specimen Type

Blood

Edp Op Specimen Type

Derived Edp Ip Buttons S

Blood, Capillary Blood, Venous Blood, Central Line Blood, Arterial

Derived Edp Ip Buttons T

Blood

Derived Edp Op Buttons S

Derived Edp Op Buttons T

Ip Orderable

Op Orderable

EPIC OP AOEs

Question ID	Question Name	Question	Response Type	Response List	Require Response
3045300170	NH IP HOME COLLECT DATE	Start Date	Date		Yes
3045300171	NH IP HOME COLLECT DAYS	Days	Custom List	Monday Tuesday Wednesday Thursday Friday Saturday Sunday	Yes
3045300173	NH IP HOME COLLECT MEDICALLY NECESSARY	Medically Necessary?	Yes/No		Yes

EPIC IP AOEs

EPIC Components (results)

Component ID	Component Name	Base Name	Common Name	External Name	Cerner Result PDM
3048100153.0	NMDA-R ABCBA	NMDARABCBA	NMDA R ABCBA		1459836A
3048100167.0	AMPHIPHYSIN AB, S	AMPHIPABS	AMPHIP AB S		1759374N
3048100159.0	CASPR2-IGG CBA, S	CASPR2IGCBAS	CASPR2 IGG CBA S		1759374D
3048100161.0	ANNA-2, S	ANNA2S	ANNA 2 S		1759374H
3048100163.0	AGNA-1, S	AGNA1S	AGNA 1 S		1759374J
3048100171.0	IFA NOTES	IFANOTES	IFA NOTES		225304B
3047804388.0	PURKINJE CELL CYTOPLASMIC AB TYPE 2	PURCYTO2	PURKINJE CELL CYTOPLASMIC AB TYPE 2		1659071F
3048100158.0	LGI1-IGG CBA, S	LGI1IGGCBAS	LGGI1 IGG CBA S		1759374C
3048100152.0	GABA-B- RECEPTOR ANTIBODY BY CBA, SERUM	GABABABCBA	GABA B ABCBA		1459835A
3048511014.0	METABOTROPIC GLUTAMATE RECEPTOR 1 AB IGG	MGLUR1ABIFA	METABOTROPIC GLUTAMATE RECEPTOR 1 AB IGG	Metabotropic glutamate receptor 1 AB IGG	1759374P
3047803748.0	NIF IFA, CSF	NIFIFA	NIF IFA, CSF		2059435B
3048100056.0	GLUTAMIC ACID DECARBOXYLASE ANTIBODY	GADAB	GLUTAMIC ACID DECARB AB		5910600
3047803754.0	NMDA-R AB CBA, CSF	NMDARABCBA	NMDA-R AB CBA, CSF		1759170B
3048511016.0	GLIAL FIBRILLARY ACIDIC PROTEIN.ALPHA SUBUNIT AB IGG	GFAPIFA	GLIAL FIBRILLARY ACIDIC PROTEIN.ALPHA SUBUNIT AB IGG	GLIAL FIBRILLARY ACIDIC PROTEIN.ALPHA SUBUNIT AB IGG	1759374Q
3048100151.0	AMPA-R ABCBA	AMPARABCBA	AMPA R ABCBA		1459833A
3048100157.0	ENCEPHALOPATHY, INTERPRETATION, S	ENCEPINTRPS	ENCEP INTERP S		1759374A
3048100160.0	ANNA-1, S	ANNA1S	ANNA 1 S		1759374F
3047804387.0	PURKINJE CELL CYTOPLASMIC AB TYPE 1	PURCYTO1	PURKINJE CELL CYTOPLASMIC AB TYPE 1		1659071E
3048100166.0	PCA-TR, S	PCATRS	PCA TR S		1759374M
3048100164.0	PCA-1, S	PCA1S	PCA 1 S		1759374K
3048100165.0	PCA-2, S	PCA2S	PCA 2 S		1759374L
3048100089.0	CRMP-5-IGG WESTERN BLOT	CR5IGWESBLOT	CR-5 IGG WES BLOT		5905943
3048511019.0	NMDAR- ABCBAC	NMDARABCBAC	NMDAR- ABCBAC	NMDAR- AbCBAC	1759170Z
3047804499.0	REFLEX ADDED	REFADD	REFLEX ADDED		1659071J
3048100162.0	ANNA-3, S	ANNA3S	ANNA 3 S		1759374I
3048511017.0	NEUROCHONDRIN AB	NEUROCHIFA	NEUROCHONDRIN AB	Neurochondrin AB	235274B
3047803728.0	NEURONAL (V-G) K+ CHANNEL AB, S	NEURONCHAN	NEURONAL (V-G) K+ CHANNEL AB, S		1759374B
3048511013.0	DIPEPTIDYL AMINOPEPTIDASE-LIKE PROTEIN 6 AB IGG	DPPXABIFA	DIPEPTIDYL AMINOPEPTIDASE-LIKE PROTEIN 6 AB IGG	Dipeptidyl aminopeptidase-like protein 6 AB IGG	235274D
3047803723.0	NEUROCHONDRIN IFA, CSF	NEURCHAB	NEUROCHONDRIN IFA, CSF		225304C

EPIC Test Compendium Alpha Welcome to the new Northwell Health Labs Test Directory, please call our Client Services Department at 1-800-472-5757 with any typos, corrections or issues.

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Encephalopathy, Autoimmune/Paraneoplastic Evaluation, Serum

Test Catalog Information

Desired Epic Build Encephalopathy, Autoimmune/Paraneoplastic Evaluation, Serum

Actual Epic build

EPIC Test Compendium Alpha
Welcome to the new Northwell Health Labs Test Directory, please call our Client Services Department at 1-800-472-5757 with any typos, corrections or issues.