Phospholipase A2 Receptor Antibody

Synonyms

• ANTI-PLA2R
• LAB10521
• PHOSPHOLIPASE A2 RESP AB
• PLA2R

Cerner Name

Phospholipase A2 Resp Ab

Clinical Info

The anti-PLA2R ELISA (IgG) test kit is intended for the qualitative or semiquantitative determination of IgG class autoantibodies against phospholipase A2 receptor (PLA2R) in human serum.1 It is used as an aid in the diagnosis of primary membranous glomerulonephritis (pMGN), in conjunction with other laboratory and clinical findings.
Limitations
The test is not a standalone test but an adjunct to other clinical information. A diagnosis of membranous nephropathy (MN) should not be made on a single test result. The clinical symptoms, results on physical examination, and laboratory tests (eg, serological tests), when appropriate, should always be taken into account when considering the diagnosis of primary versus secondary MN.
Absence of circulating PLA2R autoantibodies does not rule out a diagnosis of PLA2R-related membranous nephropathy. Clinical evidence must not be overruled in favor of a numerical value.
The assay has not been demonstrated to be effective for monitoring the stage of disease or its response to treatment.
Borderline samples should be considered as potentially positive and retested.

Specimen Sources

Blood, Arterial Blood, Capillary Blood, Central Line Blood, Venous

Specimen Types

Blood

Container

Gold Top Tube

Collection Instructions

Container/Tube:  Gold Top tube or Red Top Tube
Specimen: 0.5 mL serum (0.2 mL min)
Transport Temperature: Refrigerated
Stability: 14 Days  Room Temperature, Refrigerated or Frozen

Specimen Volume

0.5 mL serum (0.2 mL min)

Transport Instructions

Refrigerated

Specimen Stability

14 Days  Room Temperature, Refrigerated or Frozen

Methodology

Enzyme-linked immunosorbent assay (ELISA)

Days Performed

Performing Laboratory

LabCorp

CPT

83516
 
LOINC Code: 73737-9

PDM

1659078

Only Orderable at Locations:

Orderable Everywhere

Results

Result Interpretation

Forms