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Cytochrome P450 2D6 (CYP2D6) Genotype

Desired Epic Build * = editable field  

Cerner Primary Mnemonic: Cytochrome P450 2D6 Genotype
PDM 5910150
Informatics - WorkgroupMolecular-send outs
Synonyms *DME Genotyping
Display Name *Cytochrome P450 2D6 (CYP2D6) Genotype
Specimen Sources (combined Order Entry and Specimen Navigator) *
Specimen Types (combined Order Entry and Specimen Navigator) *
Blood
Body Fluids (types sent through AOEs)
Specimen Navigator Specimen Types
Specimen Navigator Specimen Sources
Specimen Navigator Short Name
Ordering info (EPIC SmartText)Cytochrome P450 2D6 (CYP2D6) is a drug-metabolizing enzyme involved in the metabolism of more than 65 clinically important drugs including some antidepressants,  anti-psychotics, opioids, beta-blockers, antiemetics, atomoxetine and tamoxifen. Individuals with some variant CYP2D6 alleles may experience a reduced therapeutic  response and may be at risk for side effects from drugs that are metabolized by CYP2D6. CYP2D6 genotype information can be utilized to predict CYP2D6 metabolic  phenotype, which can be used as an aid in determining a therapeutic strategy for drugs that are metabolized by CYP2D6.
IP Orderable (inpatient) Yes
OP Orderable (outpatient) Yes
AOEs *

AP AOEs

    
Special History No 
 
    
Build Comments

    
Filter *genetics

    
    
Cerner Site RestrictLabCorp

    
Cerner Results


                

            

                Result Desc
                Result display
                Result PDM
            

                        

                CYP2D6 Interpretation
                CYP2D6Interp
                5910150C
            

                        

                CYP2D6 Consent Review
                CYP2D6 Consent
                5910150F
            

                        

                2D6 Genotype
                CYP2D6Geno
                5910150A
            

                        

                CYP2D6 Director Review
                CYP2D6DirReview
                5910150E
            

                        

                CYP2D6 Information
                CYP2D6Info
                5910150D
            

                        

                2D6 Metabolic Activity
                CYP2D6Meta
                5910150B
            

                    

            


     





    Actual Epic Build 3/11/2025
    






                

        PROCEDURE ID
        115509
    

        

        PDM
        5910150
    

        

        ORDER DISPLAY NAME
        Cytochrome P450 2D6 (CYP2D6) Genotype
    

        

        PROCEDURE NAME
        CYTOCHROME P45 2D6 GENOTYPE
    

        

        PROCEDURE MASTER NUMBER
        LAB11597
    

        

        SHORT PROCEDURE NAME
        CYTOCHROME P45 2D6 GENOTYPE
    

        

        CATEGORY CODE
        15.0
    

        

        CATEGORY CODE RECORD NAME
        LAB CYTOGENETICS ORDERABLES
    

        

        SYNONYMS
        DME GENOTYPING
    

        

        CLINICALLY ACTIVE
        
    

        

        ORDERABLE
        
    

        

        PERFORMABLE
        
    

        

        FILTER GENOMICS
        Generic Genomics Procedure
    

        

        REFERENCE LINK URL
        https://labs.northwell.edu/epic/test/115509
    

        

        ORDERING INSTRUCTIONS
        
    

        

        DEFAULT SPECIMEN TYPE
        Blood
    

        

        SPECIMEN TYPE PICK LIST
        Blood
    

        

        SPECIMEN TYPE LIST
        
    

        

        OP SPECIMEN TYPE LIST
        
    

        

        SPECIMEN SOURCE PICK LIST
        Blood, Arterial
Blood, Capillary
Blood, Central Line
Blood, Venous		
    

        

        SPECIMEN SOURCE DEFAULT - MALE
        Blood, Venous
    

        

        SPECIMEN SOURCE DEFAULT - FEMALE
        Blood, Venous
    

        

        SPECIMEN SOURCE LIST
        
    

        

        OP SPECIMEN SOURCE LIST
        
    

        

        IP LAB TEST COMPONENTS FOR REPORT
        2D6GENOTYPE
2D6METAACT
CYP2D6INT
CYP2D6DR
CYP2D6INF
CYP2D6CR		
    

        

        OP LAB TEST COMPONENTS FOR REPORT
        2D6GENOTYPE
2D6METAACT
CYP2D6INT
CYP2D6DR
CYP2D6INF
CYP2D6CR		
    

        

        ORDER QUESTIONS
        ["3048500000"]
    

        

        ORDER QUESTIONS RECORD NAME
        
    

        

        INPATIENT ORDER QUESTIONS
        ["3048500000"]
    

        

        INPATIENT ORDER QUESTIONS RECORD NAME
        
    

        

        ORDER SPECIFIC QUESTION OVERRIDE
        
    

        

        INPATIENT QUESTION OVERRIDE
        
    

        

        LOCATION RESTRICT LIST IP
        
    

        

        LOCATION RESTRICT LIST IP RECORD NAME
        
    

        

        LOCATION RESTRICT LIST INCLUDE IP
        
    

        

        LOCATION RESTRICT LIST OP
        
    

        

        LOCATION RESTRICT LIST OP RECORD NAME
        
    

        

        LOCATION RESTRICT LIST INCLUDES OP
        
    

        

        EDP AMB ORDER SPECIFIC QUESTIONS RECORD NAME
        NH IP PATIENT COMPLETED CONSENT
    

        

        EDP IP ORDER SPECIFIC QUESTIONS RECORD NAME
        NH IP PATIENT COMPLETED CONSENT
    

        

        EDP IP SPECIMEN SOURCE
        
    

        

        EDP OP SPECIMEN SOURCE
        
    

        

        EDP IP SPECIMEN TYPE
        
    

        

        EDP OP SPECIMEN TYPE
        
    

        

        DERIVED EDP IP BUTTONS S
        
    

        

        DERIVED EDP IP BUTTONS T
        
    

        

        DERIVED EDP OP BUTTONS S
        
    

        

        DERIVED EDP OP BUTTONS T
        
    

        

        IP ORDERABLE
        1
    

        

        OP ORDERABLE
        1
    

        

        STANDARD LAB COMPONENTS
        
    

        

        STANDARD LAB COMPONENTS RECORD NAME
        
    

        

        COMPONENT DATA REQUIREMENT
        
    

    
    
EPIC OP AOEs


                

            
Question IDQuestion NameQuestionResponse TypeResponse ListRequire Response

                        

                3048500000
                NH IP PATIENT COMPLETED CONSENT
                Patient completed consent?
                Yes/No
                
                Yes
            

                    

            


    
EPIC IP AOEs


                

            
Question IDQuestion NameQuestionResponse TypeResponse ListRequire Response

                        

                3048500000
                NH IP PATIENT COMPLETED CONSENT
                Patient completed consent?
                Yes/No
                
                Yes
            

                    

            


    
EPIC Components (results - crosswalked through Cerner)


                

            
Component IDComponent NameBase NameCommon NameExternal NameCerner Result PDM

                        

                3047802089.0
                CYP2D6 INTERPRETATION
                CYP2D6INT
                CYP2D6 INTERPRETATION
                
                5910150C
            

                        

                3047802086.0
                CYP2D6 CONSENT REVIEW
                CYP2D6CR
                CYP2D6 CONSENT REVIEW
                
                5910150F
            

                        

                3047800779.0
                2D6 GENOTYPE
                2D6GENOTYPE
                2D6 GENOTYPE
                
                5910150A
            

                        

                3047802087.0
                CYP2D6 DIRECTOR REVIEW
                CYP2D6DR
                CYP2D6 DIRECTOR REVIEW
                
                5910150E
            

                        

                3047802088.0
                CYP2D6 INFORMATION
                CYP2D6INF
                CYP2D6 INFORMATION
                
                5910150D
            

                        

                3047800780.0
                2D6 METABOLIC ACTIVITY
                2D6METAACT
                2D6 METABOLIC ACTIVITY
                
                5910150B